The yeast probiotic Saccharomyces boulardii CNCM I-745 has multiple mechanisms of action for addressing diarrhea

When you have an “upset” stomach, this is an indication that your bowel might not function properly.¹

This can be due to harmful microbes such as bacteria or viruses causing damage to the lining of your gut², or because the microbiota that live in your gut and help keep normal healthy gut functioning have been disturbed, either by the infection or by non-infectious reasons such as antibiotics.¹ The disruption to your gut microbiota is called dysbiosis (an imbalance).¹ When the gut microbiota balance has been disturbed, the subsequent knock-on effect could be diarrhea.¹

The diarrhea can result from too much water being drawn into the gut, as can happen from virus and bacterial infections.² It can also occur from a disrupted microbiota that insufficiently metabolizes minerals, carbohydrates and other nutrients that are usually a source of nutrition for the normal gut microbiota, remaining in the gut along with water.¹ Also, inflammation can result from barriers between cells being damaged, which allows for electrolyte and water leakage.¹

One way to address the causes of diarrhea is by taking the yeast probiotic Saccharomyces boulardii CNCM I-745.¹

S. boulardii CNCM I-745 has several properties that make it a good probiotic.¹ a) when taken, it remains alive which means that it is actively creating a positive effect on the gut, b) has an optimal growth temperature of 37°C and c) a high tolerance to acid, such as found in the stomach.¹ Another advantage is that it does not permanently stay in the gut.¹ And, it is naturally resistant to the main prescribed antibiotics which means it can be taken at the same time as antibiotic therapy.¹

The overall effect of S. boulardii CNCM I-745 is multiple: either indirectly or directly, it improves the growth environment for the normal gut microbiota, which improves the health of the gut.¹

The yeast improves the environment by restoring the balance of microbiota, strengthens the intestinal immune system and anti-microbial activity as well as improves the gut function.¹

S. boulardii CNCM I-745 :

1. Stimulates the immune system to help the body destroy the harmful bacteria.²
2. Secretes molecules that produce an anti-inflammatory effect that reduces the amount of, and symptoms of, inflammation in the gut.³
3. Produces molecules that neutralize bacterial toxins such as cholera toxin, Clostridium difficle toxins, or Escherichia coli toxins.²
4. Interferes with harmful bacterial strains to stop them from attaching to and invading the gut cells.² It has also been reported that S. boulardii CNCM I-745 can prevent the growth of some harmful bacterial strains.²
5. Produces substances that have a positive effect on the gut cells, stimulating improved growth as well as function.³

By preventing the loss of microbiota through diarrhea and the overgrowth of harmful bacteria, S. boulardii CNCM I-745 treatment leads to a quicker restoration of the normal gut microbiota.¹

These multiple mechanisms of action support the use of S. boulardii CNCM I-745 as a therapeutical probiotic², and unlike other probiotics, it has a very broad efficacy in many different situations that can result in diarrhea.¹